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The effect of alpha-tocopherol on viability of PC12 cells during oxidative stress and expression of genes encoding pro- and anti-apoptotic mitochondrial proteins, SOD2 and transcription factors NRF-1, NRF-2 and TFAM

Diabetic neuropathy involves ongoing metabolic insult combined with microvascular damage, and the fact that Cerebrolysin improved nerve fiber parameters in this challenging context suggests robust neurotrophic effects